Scott returned to his home state in 2007 when the Titans took shape on the Gold Coast, joining forces with Luke Bailey to co-captain the inaugural team. In doing so becoming only the second player ever to play for all three Queensland teams in the top-level: Brisbane, North Queensland and Gold Coast (the first being Dale Shearer).
Prince was a star for the Gold Coast before his injury which kept him out for several weeks. Prince made a return for the Titans and they finished 12th on the ladder; one win away from the Top 8.
Prince began 2008 as co-captain with Luke Bailey. It was announced that Prince would replace the injured Darren Lockyer in the second game of the 2008 Origin series. It was initially revealed by the selectors that they were reluctant to select Prince alongside fellow halfback Johnathan Thurston in the Queensland halves as they feared that both he and Thurston would get in each other’s way during the game, however on the night both complemented each other’s game and led Queensland to a record win against the Blues (Thurston, for his part was forced to shift to five-eighth to cover for Lockyer’s loss). Having replaced Darren Lockyer, Prince himself was injured early in game three of the series, breaking his left forearm, in a game Queensland won 16–10 to win a third consecutive series. In all Prince played five Origins, for three wins and two losses.
In August 2008, Prince was named in the preliminary 46-man Kangaroos squad for the 2008 Rugby League World Cup and in October 2008 he was selected in the final 24-man Australia squad. He also played one match in the World Cup against England.
In April 2009, he was named in the preliminary 25 man squad to represent Queensland in the opening State of Origin match for 2009. Prince finished the 2009 NRL season as the fifth highest point scorer in the league, with 172 points (7 tries, 72 goals).
In 2009 Prince signed a new contract which would have kept him at the Gold Coast until 2014. However he was released from his contract at the end of the 2012 season.
Prince currently has many of the Gold Coast Titans’ individual records, such as the person with the most points scored (603), most points in a match (20) and most points in a season (182).